This role is considered Hybrid.

Overview

We are seeking an experienced and highly organized Associate Director, Global Rare Medical Project Lead to support efficient, compliant, and scalable Medical Affairs execution across Alnylam's Global Rare franchise. This role plays a key part in strengthening medical ways of working, driving operational excellence, and enabling high-quality execution of medical strategies across multiple markets. Working in close partnership with Global and Regional Medical Affairs teams, Country Medical Leads, and key cross-functional stakeholders including Compliance, Regulatory, Legal, and Patient Advocacy, you will help translate strategy into execution while ensuring consistency, efficiency, and compliance across the Global Rare organization.

This role is well suited to a proactive and structured professional who thrives in complex matrix environments, brings clarity to processes, and supports seamless delivery of global medical initiatives.

This is a hybrid office based role in Milan office, Italy and offers the opportunity to contribute to impactful medical programs in a dynamic and highly collaborative setting.

Key Responsibilities

Strategic Planning & Execution

• Coordinate and support the development and execution of Global Rare medical strategic plans, ensuring alignment with regional strategies and Expertise Areas.
• Drive strategic initiatives, monitor progress, and adjust plans to achieve objectives.
• Lead special projects and initiatives as directed by the VP, Global Rare Medical Lead.

Operational Delivery

• Oversee tactical execution of Global Rare medical initiatives, including logistics for advisory boards, contracting, and PO management.
• Develop and deliver high-quality content for presentations (QBR/MBR, leadership updates) and ensure timely follow-up on actions.
• Partner with Commercial and Medical Affairs teams to align strategies with overall rare medical objectives.

Process Optimization & Medical Excellence

• Identify and implement improvements in medical ways of working to enhance efficiency and consistency across countries.
• Develop tools, templates, workflows, and operating guidelines to support local medical execution.

Medical Review & Compliance

• Streamline Medical-Legal-Regulatory review processes to reduce cycle times and clarify roles.
• Ensure compliant execution of medical activities in line with SOPs, regulatory standards, and local codes.
• Serve as a resource for compliance and approval expectations across markets.

Cross-Functional Collaboration & Regional Representation

• Foster collaboration with clinical development, regulatory affairs, marketing, and other functions to ensure cohesive strategy execution.
• Share and coordinate insights to shape global medical processes and resource allocation.

Enablement & Team Support

• Provide hands-on support for regional medical tactics (ad boards, roundtables, data dissemination).
• Facilitate best practice sharing and capability-building across markets.

Qualifications

• Scientific degree preferred (PhD, MSc or equivalent).
• Extensive proven experience in Medical Affairs in life-science consulting or in operations and strategic roles within Global Medical Affairs in pharmaceutical/biotech organizations.
• Experience working across multiple markets and diverse regulatory environments.
• Experience in rare diseases or speciality theraoy area.
• Demonstrated ability to develop and execute medical strategies and operational plans.
• Strong written/oral communication and organizational skills, with a proven track record of leading cross-functional projects and influencing without authority.
• Ability to navigate complex organizational structures and drive flawless execution or medical plans.
• Familiarity with digital medical systems (e.g., Veeva CRM), medical dashboards, or analytics tools.
• Practical, solution-oriented approach; comfortable working in evolving, fast-paced settings
• For candidates who are not native English speakers, fluent English (written and spoken) is required.
• This position involves approximately 20% business travel.

About Alnylam: Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our culture: Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.