The Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results.

This is an exciting opportunity to play an important role to in the Brain PACT (Pediatric Accelerator of Cures for Tumors) Initiative. A critical component of high-quality pediatric brain tumor research is founded on experiments that directly study patient tumor samples or use state-of-the-art tumor models derived from patient tumors. The lab of Suzanne Baker in the Department of Developmental Neurobiology at St. Jude Children's Research Hospital is seeking a Scientist to develop 3D in vitro cultures and in vivo xenograft models directly from patient pediatric brain tumor tissue as part of the Brain PACT Initiative. This important activity will create essential new model systems for pediatric brain tumor research that will be leveraged for discovery science and preclinical testing by multiple members of the Neurobiology and Brain Tumor Program within the St. Jude Comprehensive Cancer Center. To maximize the knowledge gained through research with this precious material, this position may also process tumor tissue to provide fresh cells to research laboratories for advanced molecular studies.

The ideal candidate shows great attention to detail, is rigorous, technically skilled, and experienced with tissue culture techniques. Experience with brain tumor and/or normal neural stem cell cultures, or establishment of in vitro cultures from tissue is preferred. Experience with xenografts or in vivo models involving brain development or tumorigenesis is also advantageous.

Candidates must be highly motivated, well-organized, keep meticulous records and work effectively independently or as part of a team. A collaborative attitude is essential.

Job Responsibilities:

• Coordinates multiple aspects of research projects and carries out laboratory experiments utilizing various laboratory techniques, and determines whether additional or other tools or methods are required
• Provides input regarding research protocols and experiments. Sets up protocols and assists in developing new laboratory techniques as required.
• Identifies experimental data pertinent to the analysis problem. Processes, organizes and summarizes data, reporting these experimental results as required. Monitors quality and integrity of recorded information and data
• May draft sections of research manuscripts.
• Provides basic lab operation support to include equipment maintenance and purchasing. Monitors inventory levels and orders lab supplies as needed. Performs calibration of instruments and equipment. Troubleshoots instrument performance and equipment issues.
• Instructs other staff in basic laboratory techniques and procedures.
• Maintains regular and predictable attendance
• Performs other related duties as assigned in order to meet the goals of the department and institution

Minimum Education and/or Training:

• Bachelor's degree in relevant scientific area is required.

Minimum Experience:

• Eight (8) years of relevant work experience is required
• Six (6) years of relevant work experience is required with a Master's degree
• Three (3) years of relevant work experience is required with a PhD

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist - Pediatric Brain Tumor Model Generation.

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St. Jude is an Equal Opportunity Employer

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